THE PILOT UNIT OF ICSN - EXCELLENCE IN THE FIELD OF BIOACTIVE MICROBIAL SECONDARY METABOLITES

Philippe LOPES

philippe.lopes@cnrs.fr    
+33.1.69.82.45.57

Assistant engineer

 

Current position
Assistant engineer, ICSN, CNRS, Paris, (France)

Running projects
• EU Projects: TASCMAR H2020
• National Projects : ANR MiGenIs, ANR Enzypol

Previous work experience
• Assistant engineer, CNRS-ICSN, Gif-sur-Yvette, France, 2007
• Technician, CNRS-ICSN, Gif-sur-Yvette, France, 1996

Education
• DEST-Diploma, CNAM-Paris. Biological engineering, 2005
• General Academic Studies Degree (equivalent to Associate degree) University Paris-Sud, 1993

Fields of expertise
  • Fundamental and applied microbiology
  • Biochemistry
  • Analytical chemistry
Selected publications
  1. Agar-supported cultivation of Halorubrum sp. SSR, and production of halocin C8 on the scale-up prototype Platotex. Rima Meknaci , Philippe Lopes, Claudine Servy, Jean-Pierre Le Caer, Jean-Pierre Andrieu, Hocine Hacène, Jamal Ouazzani. Extremophiles, 2014, 18(6), 1049-1055.
  2. Isolation and characterization of α,β-unsaturated γ-lactono-hydrazides from Streptomyces sp.Géraldine Le Goff, Marie-Thérèse Martin, Claudine Servy, Sylvie Cortial, Philippe Lopes, Anne Bialecki, Jacqueline Smadja, Jamal Ouazzani.
    Journal of Natural Products. Volume 75, Issue 5, 2012, Pages 915-919.
  3. Insights into internal dynamics of 6-phosphogluconolactonase from Trypanosoma brucei studied by nuclear magnetic resonance and molecular dynamics. Calligari PA, Salgado GF, Pelupessy P, Lopes P, Ouazzani J, Bodenhausen G, Abergel D.
    Proteins. Volume 80, Issue 4, 2012, Pages1196-1210.
  4. Monitoring the dynamics of monomer exchange using electrospray mass spectrometry: the case of the dimeric glucosamine-6-phosphate synthase. Chevreux G, Atmanene C, LopeS P, Ouazzani J, Van Dorsselaer A, Badet B, Badet-Denisot MA, Sanglier-Cianférani S.
    J Am Soc Mass Spectrom. Volume 22, Issue 3, 2011, Pages 431-439.
  5. Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation. Duclert-Savatier N, Poggi L, Miclet E, Lopes P, Ouazzani J, Chevalier N, Nilges M, Delarue M, Stoven V. J Mol Biol. 2009, 388(5),1009-21.
Patents
  • OUAZZANI Jamal; SERGENT Didier; CORTIAL Sylvie; LOPES Philippe. High Pressure High temperature extractor, ZIPPERTEX. 2008 WO 2008/141943.
  • OUAZZANI Jamal; SERGENT Didier; CORTIAL Sylvie; LOPES Philippe. Universal fermentor, PLATOTEX. 2007 WO 2007/135098.